Whether transgender women take estrogen as a pill, patch, or shot doesn’t seem to make a difference in how their cholesterol and fats in the blood change over time.

41

Pro

0

Against

Evidence from Studies

Supporting (1)

41

Community contributions welcome

41

8125 Long-term Effects of Gender Affirming Hormone Therapy (GAHT) on Lipid Profile

Cohort Study

Human

The study looked at whether taking estrogen as a pill, patch, or shot changes cholesterol and fats in the blood differently — and found no difference. So, the method you use to take estrogen doesn’t affect your lipid levels.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

8125 Long-term Effects of Gender Affirming Hormone Therapy (GAHT) on Lipid Profile

Score: 41

DOI: 10.1210/jendso/bvae163.1714

Similar Assertions

For transgender women taking estrogen pills, patches, or shots for about five years, their cholesterol and fat levels in the blood don’t seem to go up or down much — even though their estrogen goes up and testosterone goes down.

41

0

79%

When transgender men take testosterone pills or shots for about four years, their cholesterol and fat levels in the blood don’t really change, even though their testosterone goes up a lot — so it seems like the hormone isn’t messing with their body’s fat and cholesterol balance.

41

0

74%