The Study
8125 Long-term Effects of Gender Affirming Hormone Therapy (GAHT) on Lipid Profile
This study watched a group of transgender people for a few years after they started hormone therapy and saw that their cholesterol and blood pressure numbers changed a little. But it didn’t compare them to people who didn’t take hormones, so we can’t say the hormones caused the changes — just that they happened together.
Analysis score
Maximum 72 for a cohort study.
Where the score came from
This study looked at what happens to people's blood numbers after they take testosterone or estrogen for years as part of gender transition.
Where does this study sit?
Systematic Reviews & Meta-analyses
Max 100Randomized Trials
Max 90Cohort Studies
Max 72Case-Control
Max 58Cross-Sectional
Max 44Case Reports & Series
Max 30Expert Opinion
Max 541 / 100
Quality score
Groups of people are followed over time to see who develops an outcome. Strong for identifying risk factors and associations, but cannot prove causation as firmly as RCTs.
Key takeaways
Summary
Based on the study abstract and findings.
- 1The changes are small and not likely to cause major health problems on their own, but doctors should still monitor blood pressure and weight.
- 2Cholesterol didn't change much.
- 3Blood pressure went up a little for trans men (72 to 76), down a little for trans women (124 to 118).
- 4Weight went up a little for trans women (BMI 28 to 30), stayed the same for trans men.
Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data
Publication
Journal
Journal of the Endocrine Society
Year
2024
Authors
Guillaume Le, S. Pinkson, Jonathan Trejo, Devjit Tripathy
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.