The Claim

In adults with chronic stroke, 12 weeks of computerized cognitive training alone has no significant effect on plasma levels of brain-derived neurotrophic factor (BDNF), C-reactive protein (CRP), or interleukin-6 (IL-6).

Source: Effects of Mindfulness and Exercise on Growth Factors, Inflammation, and Stress Markers in Chronic Stroke: The MindFit Project Randomized Clinical Trial

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
75score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Description
1 study reviewed
In plain English

Twelve weeks of computerized cognitive training does not change the blood levels of BDNF, CRP, or IL-6 in adults with chronic stroke.

See the scientific wording

In adults with chronic stroke, 12 weeks of computerized cognitive training alone does not significantly alter plasma levels of brain-derived neurotrophic factor (BDNF), C-reactive protein (CRP), or interleukin-6 (IL-6), suggesting these biomarkers are not responsive to cognitive rehabilitation in this population.

Why this might work

Doing computer-based brain exercises alone does not trigger changes in the stress hormone system or the body's inflammation signals, so levels of brain repair molecules and inflammation markers stay the same.

Verified mechanismbased on 1 study

What the research says

1 study
  1. Study: Effects of Mindfulness and Exercise on Growth Factors, Inflammation, and Stress Markers in Chronic Stroke: The MindFit Project Randomized Clinical Trial

    The study gave stroke survivors only computer-based brain exercises for 12 weeks and found that their brain repair and inflammation blood levels didn’t change. So, just doing cognitive training alone doesn’t seem to affect these biological markers.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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