mechanistic
Analysis v1
Strong Support
When your body makes less insulin (like during fasting or on a low-carb diet), it starts producing more ketones - these are alternative fuel molecules your body can use instead of sugar.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
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Fatty acid-independent inhibition of hepatic ketone body production by insulin in humans.
Cross-Sectional Study
Human
1988 JunThe study shows that when insulin is low, the liver makes more ketones, and when insulin is high, the liver makes fewer ketones - exactly matching the claim that ketone production increases as insulin decreases.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.