The Claim

The rs10735810 (FokI) genetic variant in the vitamin D receptor gene is associated with idiopathic short stature in children, with preferential transmission of the G-allele to affected individuals, suggesting that this variant may contribute to reduced stature in a subset of cases.

Source: Evidence for involvement of the vitamin D receptor gene in idiopathic short stature via a genome-wide linkage study and subsequent association studies.

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
29score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

Some kids who are much shorter than average might have a specific gene change that makes it more likely they’ll be short — and this gene change is passed down more often to those kids.

See the scientific wording

A specific genetic variant (rs10735810, FokI) in the vitamin D receptor gene is associated with idiopathic short stature in children, with preferential transmission of the G-allele to affected individuals, suggesting this variant may contribute to reduced stature in a subset of cases.

What the research says

1 study
  1. Study: Evidence for involvement of the vitamin D receptor gene in idiopathic short stature via a genome-wide linkage study and subsequent association studies.

    Scientists found that kids with unexplained short stature are more likely to inherit a specific version of a gene (called the G-allele) that helps the body use vitamin D, suggesting this gene version might be one reason some kids don’t grow as tall as others.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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