The Claim

Supplementation with L-arginine and citrulline malate is associated with a faster time to peak power during the Wingate test but does not increase peak or mean power output, indicating a limited or isolated effect on the phosphagen system.

Source: Acute effects of combined supplementation of L-arginine and citrulline malate on aerobic, anaerobic, and CrossFit exercise performance

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
71score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

How it works
1 study reviewed
In plain English

Taking L-arginine and citrulline malate supplements leads to a quicker reach of maximum power during a short, intense cycling test, but it does not result in higher maximum or average power output, suggesting the effect is restricted to the timing of power development.

See the scientific wording

The observed faster time to peak power during the Wingate test after L-arginine and citrulline malate supplementation may reflect an effect on the phosphagen system, but this does not translate to increased peak or mean power output, suggesting a limited or isolated physiological effect.

Why this might work

Supplementing with L-arginine and citrulline malate increases the amount of nitric oxide in the blood, which causes blood vessels to widen. This allows more oxygen and fuel to reach the muscles faster when they start working hard. The muscles can then use their stored energy system more quickly, reaching maximum power sooner without producing more total power.

Supported mechanismbased on 1 study

What the research says

1 study
  1. Study: Acute effects of combined supplementation of L-arginine and citrulline malate on aerobic, anaerobic, and CrossFit exercise performance

    The study found that taking these supplements helped men reach their maximum biking speed a bit faster during a short sprint, but didn’t make them pedal harder or longer — just quicker to get there.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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