Linoleic acid might make certain human ovary cells more inflamed, based on lab tests with a specific dose.

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Evidence from Studies

Supporting (1)

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Linoleic acid induces human ovarian granulosa cell inflammation and apoptosis through the ER-FOXO1-ROS-NFκB pathway

Cross-Sectional Study

In Vitro

2024 Mar 16

The study shows that linoleic acid causes inflammation in human ovarian granulosa cells, which supports the idea that it could increase inflammatory chemicals like IL-6, IL-1β, and TNF-α in these cells.

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Source Study

Linoleic acid induces human ovarian granulosa cell inflammation and apoptosis through the ER-FOXO1-ROS-NFκB pathway

Score: 6

DOI: 10.1038/s41598-024-56970-x

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