The Claim
The synthetic rates of creatine kinase M-type and carbonic anhydrase 3 in serum are strongly correlated with the synthetic rates of key muscle proteins measured in muscle biopsies, indicating that these serum proteins may serve as non-invasive biomarkers of muscle protein synthesis.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Levels of creatine kinase M-type and carbonic anhydrase 3 in the blood are closely linked to the rate at which muscle proteins are made, as measured in muscle tissue samples.
See the scientific wording
The synthetic rates of creatine kinase M-type and carbonic anhydrase 3 in serum correlate strongly with the synthetic rates of key muscle proteins measured in biopsies, suggesting these serum proteins may serve as non-invasive biomarkers of muscle protein synthesis.
When muscles grow or repair, they make more proteins inside their cells. Some of these proteins leak into the blood, and the rate at which they are made in the blood matches exactly how fast they are made in the muscle. This means measuring these proteins in the blood gives the same information as taking a muscle sample.
What the research says
1 studyThis study found that two proteins in the blood (CK-M and CA-3) go up and down at the same time as muscle proteins do when people do resistance training — meaning these blood proteins might be a simple way to tell how fast muscles are growing, without needing a biopsy.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.