The Claim

In resistance-trained men, high-volume resistance training (10–12 repetitions at approximately 70% of one-repetition maximum with 1-minute rest intervals) induces a greater acute growth hormone response during early training (week 3) compared to high-intensity resistance training (3–5 repetitions at approximately 90% of one-repetition maximum with 3-minute rest intervals), but this difference is no longer evident by week 10.

Source: The effect of training volume and intensity on improvements in muscular strength and size in resistance-trained men

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
54score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

How it works
1 study reviewed
In plain English

In guys who lift weights regularly, doing more reps with lighter weights and short breaks gives a bigger boost in growth hormone early on (by week 3) than doing fewer reps with heavier weights and longer breaks—but by week 10, that difference goes away.

See the scientific wording

In resistance-trained men, high-volume resistance training (10–12RM at ~70% 1RM with 1-minute rest) elicits a greater acute growth hormone response during early training (week 3) compared to high-intensity training (3–5RM at ~90% 1RM with 3-minute rest), but this difference diminishes by week 10.

What the research says

1 study
  1. Study: The effect of training volume and intensity on improvements in muscular strength and size in resistance-trained men

    The study found that lighter weights with more reps caused a bigger spike in growth hormone early on, but that effect got smaller after 10 weeks, just like the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

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