mechanistic
Analysis v1
Strong Support
If you're a guy who lifts weights, taking creatine won't make you hold more water outside your cells compared to just training — the water increase seems to come from working out, not the supplement.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
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Creatine Supplementation Does Not Influence the Ratio Between Intracellular Water and Skeletal Muscle Mass in Resistance-Trained Men.
Randomized Controlled Trial
Human
2020 Nov 1The study shows that both creatine and placebo groups had the same increase in extracellular water after training, so creatine didn’t add extra fluid gain beyond what exercise alone caused.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.