Liver cells from female rats that were trained for endurance produce way more sugar when triggered by a stress hormone, compared to liver cells from untrained rats — showing their bodies are better tuned to respond under stress.

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Evidence from Studies

Supporting (1)

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Enhanced glucose production in norepinephrine and palmitate stimulated hepatocytes following endurance training

Cross-Sectional Study

Animal

2024

The study looked at liver cells from trained and untrained rats and found that the trained cells made much more glucose when exposed to norepinephrine, just like the claim says.

Contradicting (0)

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No contradicting evidence found

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Source Study

Enhanced glucose production in norepinephrine and palmitate stimulated hepatocytes following endurance training

Score: 15

DOI: 10.3389/fphys.2024.1514082

Similar Assertions

After 10 weeks of endurance training, female rat liver cells become more sensitive to a stress hormone called norepinephrine, meaning they start producing more sugar with much smaller amounts of the hormone compared to untrained rats.

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Female rats that did treadmill training for 10 weeks made more glucose in their liver cells, even when resting and without hormones, compared to rats that didn’t train.

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In female rats that were trained for endurance, their liver cells used more lactate to make glucose when stimulated, and this extra fuel use completely explains why they made more glucose—meaning the key change was how much lactate got into the cells, not how fast the cells processed it.

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