People born with a broken PCSK9 gene have much healthier hearts.
Evidence from Studies
Supporting (3)
Community contributions welcome
Sequence variations in PCSK9, low LDL, and protection against coronary heart disease.
People born with certain mutations in the PCSK9 gene have lower 'bad' cholesterol and are much less likely to get heart disease, which is exactly what this study found.
The study looks at people with natural PCSK9 gene changes that lower bad cholesterol, and finds they have a lower chance of heart disease, which supports the claim.
Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9
The study found that people with broken versions of the PCSK9 gene have much lower 'bad' cholesterol, which helps protect against heart disease—just like the claim says.
Contradicting (0)
Community contributions welcome
Score Breakdown
No multi-axis breakdown available yet. The overall Pro / Against score above is the best signal.
- No clinical evidence is available; the score reflects mechanistic plausibility only.
