mechanistic
Analysis v1
Strong Support
Young guys need their natural testosterone to get the full muscle-building benefits from weightlifting — if their testosterone is blocked with drugs, their muscles don’t grow as much, even if they train just as hard.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
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Pharmacological hypogonadism impairs molecular transducers of exercise‐induced muscle growth in humans
Randomized Controlled Trial
Human
2022 AprThe study shows that when testosterone is lowered with drugs, young men don’t build muscle as well during training, which supports the idea that normal testosterone levels are needed for muscle growth.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.