mechanistic
Analysis v1
Strong Support
Young men with low testosterone don't get the same muscle-building boost from weight training because their bodies don't increase the machinery needed to make new proteins — and that seems to be because they're missing testosterone.
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0
Evidence from Studies
Supporting (1)
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Community contributions welcome
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Pharmacological hypogonadism impairs molecular transducers of exercise‐induced muscle growth in humans
Randomized Controlled Trial
Human
2022 AprThe study shows that when young men have low testosterone, their muscles don’t respond as well to weight training in terms of building the machinery needed for growth, which supports the idea that testosterone is important for this process.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.