The Claim
Testosterone is required for resistance training-induced increases in ribosomal biogenesis, as evidenced by changes in the RNA:DNA ratio, since hypogonadal young men show no significant increase in this marker following resistance training compared to placebo-treated individuals who exhibit a significant rise.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Young men with low testosterone don't get the same muscle-building boost from weight training because their bodies don't increase the machinery needed to make new proteins — and that seems to be because they're missing testosterone.
See the scientific wording
Resistance training-induced increases in ribosomal biogenesis, measured by RNA:DNA ratio, are blunted in hypogonadal young men, with placebo recipients increasing RNA:DNA from 0.50 ± 0.01 to 0.64 ± 0.04 (P = 0.003) while hypogonadal men show no significant change (0.47 ± 0.03 to 0.53 ± 0.03, P = 0.31), indicating testosterone is required for exercise-induced expansion of translational capacity.
What the research says
1 studyThe study shows that when young men have low testosterone, their muscles don’t respond as well to weight training in terms of building the machinery needed for growth, which supports the idea that testosterone is important for this process.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.