When young men have low testosterone on purpose for the study, their muscles don’t respond as well to weight training at the cellular level — testosterone seems to help muscles fully 'feel' and react...

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Against

Evidence from Studies

Supporting (1)

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Pharmacological hypogonadism impairs molecular transducers of exercise‐induced muscle growth in humans

Randomized Controlled Trial

Human

2022 Apr

Contradicting (0)

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No contradicting evidence found

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Source Study

Pharmacological hypogonadism impairs molecular transducers of exercise‐induced muscle growth in humans

Score: 74

DOI: 10.1002/jcsm.12843

Similar Assertions

If young guys are given a drug that lowers their testosterone, they don’t build much muscle from weight training—while others with normal testosterone gain about 1.5 kg of muscle in 6 weeks. This shows testosterone is key for getting the most out of lifting weights.

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When young men eat way less food than usual, giving them a high dose of testosterone makes some muscle-building signals in their cells stronger, but it doesn’t stop their muscles from breaking down — just like in guys who get a fake pill.

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