Taking melatonin supplements may lower your blood pressure, blood sugar, and bad cholesterol, while also reducing inflammation and boosting your body's natural antioxidants.
Evidence from Studies
Supporting (3)
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Comprehensive Effects of Melatonin Supplementation on Cardiometabolic Risk Factors: A Systematic Review and Dose–Response Meta-Analysis
A large review of many studies shows that melatonin supplements help lower bad cholesterol, improve blood sugar control, reduce body-wide inflammation, and boost the body's natural antioxidant defenses.
Research combining multiple clinical trials confirms that taking melatonin supplements effectively lowers both the top and bottom numbers of blood pressure in people with metabolic conditions.
Contradicting (2)
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This study found that melatonin supplements do not significantly improve how the body processes sugar or insulin, contradicting the claim that they lower blood glucose and other health markers.
This study found that taking melatonin did not lower blood pressure or improve blood sugar control in night shift workers, which goes against the claim that it significantly reduces these health markers.
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.