Taking melatonin supplements seems to help your body's relaxation system work better, which shows up as a healthier heart rate pattern, especially when you're resting or sleeping. This effect is seen in both healthy people and those with heart or brain conditions.

Our current analysis suggests that melatonin may help improve heart rate patterns linked to relaxation. We found that the evidence leans toward melatonin supporting the body's rest-and-digest functions. We analyzed the available research and found 1 studies support, 0 studies refute this idea. Our review indicates that taking melatonin supplements seems to help your body's relaxation system work better [1]. This effect appears as a healthier heart rate pattern, particularly when you are resting or sleeping [1]. We also noted that this pattern shows up in both healthy individuals and people with heart or brain conditions [1]. The relaxation system refers to the parasympathetic nervous system, which helps your body calm down and recover after stress. Heart rate variability measures the small changes in time between your heartbeats, which can show how well your body handles stress and maintains balance. What we've found so far points in one direction, but we only have a small amount of data. Our analysis is based on limited evidence, so this view might change as more research becomes available. We do not have enough evidence to say how strong this effect is or how it applies to every situation. Our current analysis shows a positive trend, but we are still gathering information to give you a clearer picture over time. We encourage you to check back as we continue to review new studies. In everyday terms, melatonin might help your body switch into a calmer state, which could be good for your heart health when you are resting.