Taking L-carnitine with carbs for 12 weeks might turn up the activity of 73 genes that help the body burn fuel better — especially those involved in how insulin works and how fats are used — in healthy young guys, compared to just taking carbs.

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Evidence from Studies

Supporting (1)

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Community contributions welcome

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Skeletal muscle carnitine loading increases energy expenditure, modulates fuel metabolism gene networks and prevents body fat accumulation in humans

Randomized Controlled Trial

Human

2013 Sep 15

The study shows that taking L-carnitine with carbs for 12 weeks changed how the body burns fuel in healthy young men, turning on 73 genes linked to fat burning and insulin, just like the claim says.

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Skeletal muscle carnitine loading increases energy expenditure, modulates fuel metabolism gene networks and prevents body fat accumulation in humans

Score: 45

DOI: 10.1113/jphysiol.2013.255364

Similar Assertions

If healthy young guys take L-carnitine and carbs for 12 weeks, they might burn 6% more energy during light workouts — mostly by burning more fat, not carbs.

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78%

If healthy young guys take L-carnitine with carbs twice a day for 12 weeks, they don’t gain the extra body fat that usually comes from just taking carbs — even though both groups are eating more calories than they need.

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76%

If healthy young guys take a certain amount of L-carnitine with carbs every day for 12 weeks, they might store more carnitine in their muscles, burn more energy during light exercise, and avoid gaining fat compared to just taking carbs.

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75%