The Claim

In young, healthy males, consuming 5 grams of creatine with either 95 grams of dextrose or a mixture of 14 grams of protein hydrolysate, 7 grams of leucine, 7 grams of phenylalanine, and 57 grams of dextrose results in lower 24-hour urinary creatine excretion compared to consuming the same dose of creatine with water alone.

Source: Optimization of insulin-mediated creatine retention during creatine feeding in humans

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
46score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Quantitative
1 study reviewed
In plain English

If young, healthy guys take creatine with sugary drinks or a special mix of protein and sugar, less creatine comes out in their pee over 24 hours compared to taking it with just water.

See the scientific wording

In young, healthy males, 24-hour urinary creatine excretion is lower when 5 g creatine is consumed with 95 g dextrose or with 14 g protein hydrolysate, 7 g leucine, 7 g phenylalanine, and 57 g dextrose compared to when taken with water alone.

What the research says

1 study
  1. Study: Optimization of insulin-mediated creatine retention during creatine feeding in humans

    The study found that when young men took creatine with sugar or with a mix of protein and sugar, they lost less creatine in their urine than when they took it with water alone, which supports the claim.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.