Premenopausal Mexican women tend to have lower levels of a certain estrogen-related marker in their urine compared to other groups, and this might mean they're at higher risk for breast cancer because lower levels of this marker are linked to more cancer cases.

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Evidence from Studies

Supporting (1)

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Community contributions welcome

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Effectiveness of 3,3′-Diindolylmethane Supplements on Favoring the Benign Estrogen Metabolism Pathway and Decreasing Body Fat in Premenopausal Women

Randomized Controlled Trial

Human

2023

The study found that Mexican women naturally have lower levels of a certain estrogen ratio in their urine, which is linked to higher breast cancer risk, supporting the claim.

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Effectiveness of 3,3′-Diindolylmethane Supplements on Favoring the Benign Estrogen Metabolism Pathway and Decreasing Body Fat in Premenopausal Women

Score: 54

DOI: 10.1080/01635581.2022.2123535

Similar Assertions

Taking a supplement called DIM every day for a month doesn’t seem to change a certain hormone balance in premenopausal Mexican women that’s linked to lower breast cancer risk — but there might be a slight improvement a month after stopping.

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