Mice given thyroxine eat nearly twice as much food to keep up with their faster metabolism, but even after accounting for the energy used to digest that food, their metabolism is still much higher —...

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Against

Evidence from Studies

Supporting (1)

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At thermoneutrality, acute thyroxine-induced thermogenesis and pyrexia are independent of UCP1

Case-Control Study

Animal

2019 Jul

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

At thermoneutrality, acute thyroxine-induced thermogenesis and pyrexia are independent of UCP1

Score: 13

DOI: 10.1016/j.molmet.2019.05.005