The Claim
In adult female mice undergoing progressive weighted wheel running, both frequent (2 mg/kg, 3 times per week) and intermittent (2 mg/kg, once per week) rapamycin dosing impair glucose tolerance compared to vehicle control, with intermittent dosing resulting in less severe glucose intolerance, suggesting a partial protective effect of less frequent administration.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
In female mice that run with added weight, taking a drug called rapamycin makes it harder for their bodies to handle sugar — but doing it less often doesn't hurt as much, so spacing out doses might help reduce the downside.
See the scientific wording
In adult female mice performing progressive weighted wheel running, both frequent and intermittent rapamycin dosing (2mg/kg 3x/week or 1x/week) impair glucose tolerance compared to vehicle control, but intermittent dosing results in less severe glucose intolerance, indicating a partial protective effect of less frequent administration.
What the research says
1 studyThe study found that giving rapamycin once a week or three times a week made mice less able to handle sugar, but once-a-week caused less harm than three times a week, which matches the claim.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.