In male mice eating 40% fewer calories, the type of fat they eat matters — mice live longer on more saturated fats like lard than on unsaturated fats like soybean or fish oil.

8

Pro

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Against

Evidence from Studies

Supporting (1)

8

Community contributions welcome

8

The Impact of Aging, Calorie Restriction and Dietary Fat on Autophagy Markers and Mitochondrial Ultrastructure and Dynamics in Mouse Skeletal Muscle.

Cross-Sectional Study

Animal

2019 May 16

The study found that male mice on a very low-calorie diet lived longer when they ate more saturated fat (like lard) compared to unsaturated fats (like in soybean or fish oil), which supports the claim.

Contradicting (0)

0

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

The Impact of Aging, Calorie Restriction and Dietary Fat on Autophagy Markers and Mitochondrial Ultrastructure and Dynamics in Mouse Skeletal Muscle.

Score: 8

DOI: 10.1093/gerona/gly161

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