Lots of obese women who aren't diabetic feel nauseous when they start taking a drug called exenatide for weight loss — about 56 out of every 100. But the queasiness usually gets better over time, and how much weight they lose doesn’t seem to depend on how bad the nausea is.

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Evidence from Studies

Supporting (1)

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Community contributions welcome

56

Short-Term Exenatide Treatment Leads to Significant Weight Loss in a Subset of Obese Women Without Diabetes

Randomized Controlled Trial

Human

2012 Jan

The study looked at the same medicine and people described in the claim, and found that nausea was common, got better over time, and didn’t affect how much weight people lost.

Contradicting (0)

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No contradicting evidence found

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According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Short-Term Exenatide Treatment Leads to Significant Weight Loss in a Subset of Obese Women Without Diabetes

Score: 56

DOI: 10.2337/dc11-0931

Similar Assertions

Even if obese women lose weight on a drug called exenatide, their metabolism doesn’t slow down like it usually does when people lose weight from dieting — so this drug might skip the usual 'metabolic slowdown' people hit.

56

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73%

Taking a drug called exenatide twice a day for about four months helps obese women who don’t have diabetes lose around 2.5 kilograms on average, and they start seeing results in just two weeks.

56

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71%

Some women who are obese but don’t have diabetes lose a good amount of weight on a drug called exenatide for 16 weeks, but almost as many actually gain weight — showing it works very differently from person to person.

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70%