MOTS-c made mouse cells break down more fat for fuel, as shown by higher levels of fat-burning byproducts and lower levels of stored fats.

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Against

Evidence from Studies

Supporting (0)

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Community contributions welcome

No supporting evidence found

Contradicting (1)

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Community contributions welcome

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The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance

Randomized Controlled Trial

Animal

2015 Mar 3

The study says MOTS-c helps mice stay healthy and not get fat, but it never measured the specific fat breakdown products or fatty acid levels mentioned in the claim, so we can't say for sure that part is true.

Source Study

The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance

Score: 13

DOI: 10.1016/j.cmet.2015.02.009

Similar Assertions

Mice that ate a fatty diet and got daily MOTS-c shots didn’t get as fat as mice that didn’t get the shots—even though they ate the same amount of food.

13

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72%

MOTS-c injections in obese mice reduced a type of fat molecule called 2-oleoylglycerol by about 32% compared to untreated mice.

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70%