The Claim

In primary human skeletal muscle myoblasts, treatment with 100 nM of active vitamin D (1,25(OH)2D) for 24 hours increases oxygen consumption rate, and in primary human skeletal muscle myotubes, treatment with 100 nM of active vitamin D (1,25(OH)2D) for 5 days increases oxygen consumption rate.

Source: Effects of vitamin D on primary human skeletal muscle cell proliferation, differentiation, protein synthesis and bioenergetics.

What the research says

Roughly balanced

Support and challenge are close. The picture may shift as more studies come in.

Supports
3score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Cause and effect
1 study reviewed
In plain English

When you give human muscle cells a specific form of vitamin D, they start using more oxygen — but only after 24 hours if they’re young cells, and after 5 days if they’ve turned into mature muscle fibers.

See the scientific wording

In primary human skeletal muscle myoblasts, treatment with 100 nM of active vitamin D (1,25(OH)2D) for 24 hours increases oxygen consumption rate, and in myotubes, this increase is observed after 5 days of treatment.

What the research says

1 study

  1. Study: Effects of vitamin D on primary human skeletal muscle cell proliferation, differentiation, protein synthesis and bioenergetics.

    The study gave human muscle cells the same vitamin D dose and for the same amount of time as the claim, and found that the cells used more oxygen — just like the claim said they would.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.