Some muscles might respond differently to how you stretch them during exercise, depending on how they’re built.

The hypertrophic response to training at longer muscle lengths may differ between untrained and trained individuals, but current evidence is insufficient to determine this due to limited data in trained populations.

Individual hypertrophic responses to resistance training are highly variable across muscle groups and are not consistently correlated between upper and lower body musculature.

Everyone’s body responds differently to workouts—what works wonders for one person might be too much or too little for another, because of differences in genes, energy use, and how fast they recover.

When people gain muscle from resistance training, the amount of growth varies between muscles, and these differences are partly linked to how similar the responses are across muscles, but much of the variation comes from personal biological traits unrelated to the workout itself.

Total training volume, training intensity, and consistency are more significant determinants of muscle hypertrophy than the specific muscle length at which training occurs.