The Claim

Nicotinamide riboside (NR) supplementation at tested doses did not significantly extend lifespan in genetically heterogeneous mice, with results consistent across three independent testing sites over a 5-year study period.

Source: The Anti-Aging Supplement Scam (New Evidence)

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
13score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Cause and effect
2 studies reviewed
In plain English

A popular anti-aging supplement called nicotinamide riboside (NR) was given to mice to see if it could help them live longer, but the study found it didn't extend their lifespan at the doses tested.

See the scientific wording

Nicotinamide riboside (NR), a supplement marketed to boost NAD+ levels and combat aging, showed no significant lifespan extension in genetically heterogeneous mice at tested doses, with results consistent across three independent testing sites over 5 years.

What the research says

2 studies
  1. Study: 17‐a‐estradiol late in life extends lifespan in aging UM‐HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex

    The study gave nicotinamide riboside (NR) to genetically diverse mice and found it did not make them live longer. This matches exactly what the claim says about NR not extending lifespan in these mice.

  2. Study: 17‐a‐estradiol late in life extends lifespan in aging UM‐HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex

    The study gave nicotinamide riboside (NR) to genetically mixed mice and found it did NOT make them live longer. This matches exactly what the claim says - that NR didn't extend lifespan in these types of mice.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 2 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

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