The Claim

In obese adults who lost 13.1 kg via a low-calorie diet, one year of supervised exercise combined with liraglutide 3.0 mg daily resulted in a net 5.1 kg greater weight reduction one year after treatment cessation compared to liraglutide alone.

Source: Healthy weight loss maintenance with exercise, GLP-1 receptor agonist, or both combined followed by one year without treatment: a post-treatment analysis of a randomised placebo-controlled trial

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
68score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Cause and effect
1 study reviewed
In plain English

Obese adults who lost 13.1 kg on a low-calorie diet and then exercised with daily liraglutide 3.0 mg for one year lost an additional 5.1 kg more one year after stopping treatment than those who took liraglutide alone.

See the scientific wording

In obese adults who lost 13.1 kg via a low-calorie diet, one year of supervised exercise combined with liraglutide 3.0 mg daily resulted in a net 5.1 kg greater weight reduction one year after treatment cessation compared to liraglutide alone, suggesting that exercise enhances long-term weight maintenance beyond pharmacotherapy effects.

Why this might work

After weight loss, the body slows down metabolism and increases hunger to regain lost weight. Exercise trains the body to keep burning more calories every day, even after the exercise program ends. This higher calorie burn counters the body's natural drive to regain weight, so the person stays lighter long after stopping medication.

Verified mechanismbased on 1 study

What the research says

1 study
  1. Study: Healthy weight loss maintenance with exercise, GLP-1 receptor agonist, or both combined followed by one year without treatment: a post-treatment analysis of a randomised placebo-controlled trial

    People who lost weight with a diet, then added daily exercise along with a weight-loss drug, kept off 5.1 kg more after stopping the drug than people who only took the drug. Exercise helped them hold onto their weight loss better.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

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