The Claim

In obese adults, implementation of a protein-sparing modified fast (PSMF) or phase 3 weight reduction plan is associated with significant weight loss over 20 weeks, but no significant weight maintenance is observed, with weight gradually regained and all initial loss reversed by two years.

Source: Short-Term and Long-Term Effects of Weight Reduction Programs Offered at the Guthrie Clinic

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
24score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

Obese adults who follow a protein-sparing modified fast or phase 3 weight loss plan lose weight in the first 20 weeks, but regain all the lost weight by two years.

See the scientific wording

In obese adults, protein-sparing modified fast (PSMF) and phase 3 weight reduction plans are associated with significant short-term weight loss over 20 weeks, but no significant long-term weight maintenance is observed, with weight gradually regained and all significant loss reversed by two years.

Why this might work

When calorie intake drops sharply, the body slows down its energy use, lowers key hunger-suppressing hormones, and increases hunger signals. This makes the body burn fewer calories and crave more food, causing weight to return even after eating normally again.

Supported mechanismbased on 1 study

What the research says

1 study
  1. Study: Short-Term and Long-Term Effects of Weight Reduction Programs Offered at the Guthrie Clinic

    People who followed a high-protein, low-calorie diet or a phased weight loss plan lost weight quickly in the first few months, but they all gained it all back by two years — just like the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.