Obese adults with type 2 diabetes have slower muscle energy production rates after exercise compared to those without diabetes, as measured by oxidative phosphorylation.
Scientific Claim
Type 2 diabetes is associated with slower oxidative phosphorylation rates during recovery from isometric calf exercise in sedentary obese adults (P=0.046).
Original Statement
“in vivo mitochondrial oxidative phosphorylation capacity measured in the gastrocnemius muscle via 31P-MRS indicated an impairment in the rate of ADP depletion with rest (27 ± 6 s [diabetes], 21 ± 7 s [control subjects]; P = 0.008) and oxidative phosphorylation (P = 0.046) in type 2 diabetes after isometric calf exercise compared with control subjects.”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The study design is observational but allows for association claims between groups. The verb 'associated with' correctly reflects the evidence.
Evidence from Studies
Supporting (1)
Supplemental Oxygen Improves In Vivo Mitochondrial Oxidative Phosphorylation Flux in Sedentary Obese Adults With Type 2 Diabetes