People with type 2 diabetes who are sedentary and obese take longer to recover their muscle energy levels after exercise compared to obese people without diabetes, as measured by how quickly their muscles use up ADP.
Scientific Claim
In sedentary obese adults, type 2 diabetes is associated with slower ADP depletion rates during recovery from isometric calf exercise (27 ± 6 seconds in the diabetes group vs 21 ± 7 seconds in the control group; P=0.008).
Original Statement
“in vivo mitochondrial oxidative phosphorylation capacity measured in the gastrocnemius muscle via 31P-MRS indicated an impairment in the rate of ADP depletion with rest (27 ± 6 s [diabetes], 21 ± 7 s [control subjects]; P = 0.008) and oxidative phosphorylation (P = 0.046) in type 2 diabetes after isometric calf exercise compared with control subjects.”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The study design is observational but allows for association claims between groups. The verb 'associated with' correctly reflects the evidence.
Evidence from Studies
Supporting (1)
Supplemental Oxygen Improves In Vivo Mitochondrial Oxidative Phosphorylation Flux in Sedentary Obese Adults With Type 2 Diabetes