The Claim

In adults aged 65 and older with a history of cardiovascular disease, daily supplementation with Centrum Silver multivitamin-mineral for three years is associated with a larger improvement in global cognitive function (mean z=0.14) compared to adults aged 65 and older without a history of cardiovascular disease (mean z=0.06).

Source: Effects of cocoa extract and a multivitamin on cognitive function: a randomized clinical trial

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
80score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

Among adults aged 65 and older, those with a history of cardiovascular disease who took Centrum Silver daily for three years showed a greater improvement in cognitive function than those without cardiovascular disease who took the same supplement.

See the scientific wording

In adults aged 65 and older with a history of cardiovascular disease, daily supplementation with Centrum Silver multivitamin-mineral for three years is associated with a larger improvement in global cognitive function (mean z=0.14) compared to those without cardiovascular disease (mean z=0.06), suggesting a potentially greater benefit in higher-risk individuals.

Why this might work

In older adults with heart disease, daily multivitamin supplements raise levels of key nutrients like B vitamins, vitamin D, and selenium, which lower harmful oxidative stress and inflammation in the brain. This allows brain cells to produce energy more efficiently, repair damage, and form stronger connections, leading to better memory and thinking skills.

Supported mechanismbased on 1 study

What the research says

1 study
  1. Study: Effects of cocoa extract and a multivitamin on cognitive function: a randomized clinical trial

    In a big study, older adults with heart disease who took a daily multivitamin like Centrum Silver showed a bit better memory and thinking after three years than those without heart disease—suggesting the vitamin might help those at higher risk more.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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