A specific spot in a protein called MCT8, kind of like a tiny switch, seems really important for how it works — if that spot gets damaged, the protein can't do its job moving stuff in and out of cells.

Evidence from Studies

Supporting (1)

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Insights into molecular properties of the human monocarboxylate transporter 8 by combining functional with structural information

Computational/Algorithm Study

2011 Aug 3

The study shows that important parts of the MCT8 protein, especially in certain loops, are sensitive to changes, and messing with them stops the protein from working—just like the claim says.

Contradicting (0)

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No contradicting evidence found

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Source Study

Insights into molecular properties of the human monocarboxylate transporter 8 by combining functional with structural information

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DOI: 10.1186/1756-6614-4-S1-S4

Similar Assertions

If certain parts of a protein called MCT8 get mutated—especially in specific twisted sections—those changes might bend the protein the wrong way and break how it works, kind of like a kink in a hose.

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77%

Harmful spelling mistakes in a brain-related protein called MCT8 only show up in certain tightly packed parts of the protein, especially in spots that haven’t changed much over time — suggesting these spots are really important for how the protein works.

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75%