When your body processes green tea, it changes the main active ingredient in two different ways—like adding a sugar tag in two different spots. One version keeps its power to block a specific enzyme, but the other doesn’t. So where the sugar tag sticks makes all the difference.

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Pro

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Against

Evidence from Studies

Supporting (1)

20

Community contributions welcome

20

Enzymology of methylation of tea catechins and inhibition of catechol-O-methyltransferase by (-)-epigallocatechin gallate.

Cross-Sectional Study

Human

2003 May

The study found that when a chemical from green tea is changed at one specific spot (3'-O), it still works as well at blocking an enzyme, but when changed at another spot (4"-O), it doesn’t work as well — just like the claim said.

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Enzymology of methylation of tea catechins and inhibition of catechol-O-methyltransferase by (-)-epigallocatechin gallate.

Score: 20

DOI: 10.1124/DMD.31.5.572

Similar Assertions

When your body adds a sugar-like group to certain parts of the green tea compound EGCG, it can block another chemical change that would normally happen—but only if it’s added to specific spots. If it’s added to the right spot, the other change still works fine.

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