When your body adds a sugar-like group to certain parts of the green tea compound EGCG, it can block another chemical change that would normally happen—but only if it’s added to specific spots. If it’s added to the right spot, the other change still works fine.

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Evidence from Studies

Supporting (1)

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Community contributions welcome

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Enzymology of methylation of tea catechins and inhibition of catechol-O-methyltransferase by (-)-epigallocatechin gallate.

Cross-Sectional Study

Human

2003 May

When tea compounds are modified at certain spots (B-ring or D-ring), they can't be methylated anymore — but if modified at the A-ring, methylation still happens. The study proved this exact pattern.

Contradicting (0)

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No contradicting evidence found

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According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Enzymology of methylation of tea catechins and inhibition of catechol-O-methyltransferase by (-)-epigallocatechin gallate.

Score: 20

DOI: 10.1124/DMD.31.5.572

Similar Assertions

When your body processes green tea, it changes the main active ingredient in two different ways—like adding a sugar tag in two different spots. One version keeps its power to block a specific enzyme, but the other doesn’t. So where the sugar tag sticks makes all the difference.

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