The Claim

The rs10735810 single nucleotide polymorphism in the vitamin D receptor gene may account for up to 34% of cases of idiopathic short stature in the population, based on linkage and transmission data from familial cohorts.

Source: Evidence for involvement of the vitamin D receptor gene in idiopathic short stature via a genome-wide linkage study and subsequent association studies.

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
29score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Quantitative
1 study reviewed
In plain English

A specific gene variation called rs10735810 might be behind as much as one in three cases of unexplained short height in kids, based on studies of families where this trait runs in the bloodline.

See the scientific wording

The rs10735810 SNP in the vitamin D receptor gene may account for up to 34% of idiopathic short stature cases in the population, based on linkage and transmission data from familial cohorts.

What the research says

1 study

  1. Study: Evidence for involvement of the vitamin D receptor gene in idiopathic short stature via a genome-wide linkage study and subsequent association studies.

    Scientists found that a specific gene variation (rs10735810) in the vitamin D receptor is passed down more often to children who are very short for no clear reason, and they think this one gene change might explain about one in three of these cases.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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