People who work irregular shifts tend to gain weight, and that extra weight explains about a third of why they’re more likely to have fat in their liver—but other factors also play a role.

Evidence from Studies

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Shift work and metabolic dysfunction-associated steatotic liver disease: a systematic review of observational studies

Systematic Review

Human

2025 Dec

The study says shift work might lead to more liver fat partly because people gain weight, but it doesn’t say how much of that effect is due to weight gain — so it can’t confirm the claim that it’s exactly 30–36%.

Gold Standard Evidence Needed

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Source Study

Shift work and metabolic dysfunction-associated steatotic liver disease: a systematic review of observational studies

Score: 52

DOI: 10.1007/s00420-025-02171-6

Similar Assertions

People who work nights or irregular shifts are more likely to develop a fatty liver condition, especially if they do it for a long time or often — this might be because their body’s internal clock gets messed up.

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