When you only get 4 hours of sleep, your body’s immune cells get activated in a way that causes inflammation, and this happens even if your stress hormone levels don’t change.

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Evidence from Studies

Supporting (1)

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Sleep loss activates cellular inflammatory signaling.

Randomized Controlled Trial

Human

2008 Sep 15

When people don’t get enough sleep—like only sleeping 4 hours—your immune cells get activated in a way that causes inflammation, even if your stress hormones don’t change. This study showed that happening in people who stayed up late.

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