Some cholesterol drugs called PCSK9 inhibitors also lower another harmful fat in the blood called lipoprotein(a), and that might help protect the heart in ways that aren't just about lowering bad cholesterol.

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Evidence from Studies

Supporting (1)

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Community contributions welcome

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PCSK9 Inhibition: Insights From Clinical Trials and Future Prospects

Narrative Review

In Vitro

2020

The study shows that PCSK9 drugs lower bad cholesterol and reduce heart risks, which fits the general idea in the claim, but it doesn’t fully prove how much they lower Lp(a) or that this directly cuts heart risk on its own.

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

PCSK9 Inhibition: Insights From Clinical Trials and Future Prospects

Score: 1

DOI: 10.3389/fphys.2020.595819

Similar Assertions

Some cholesterol-lowering drugs called PCSK9 inhibitors can lower a specific type of blood fat linked to heart disease, and that might help protect people with high levels, but scientists aren't sure exactly how it works yet.

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90%

PCSK9 inhibitors can help lower bad cholesterol, either when added to other treatments or used instead of them.

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These cholesterol drugs, called PCSK9 inhibitors, probably help lower bad cholesterol in many types of patients — more than fake pills or other cholesterol medicines.

20

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These cholesterol drugs work well for lots of different people, even if they're already taking other meds for high cholesterol.

20

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Adding PCSK9 drugs to cholesterol-lowering statins can slash bad cholesterol by as much as 81% in people with high cholesterol.

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85%