People who naturally have lower 'bad' cholesterol because of their genes tend to have cleaner arteries, which means less buildup of plaque over time.

People born with a certain gene change that breaks the PCSK9 gene tend to have much lower 'bad' cholesterol their whole lives and are far less likely to get heart disease — so scientists think blocking this gene with medicine might help protect others' hearts too.

People who naturally have a broken PCSK9 gene — which keeps their bad cholesterol low their whole life — are much less likely to get heart disease, and this seems to be true for people of many different backgrounds.

People born with a certain gene that lowers their bad cholesterol their whole life have a lower risk of heart disease than what we'd expect from cholesterol-lowering drugs like statins — meaning starting early and keeping cholesterol low for longer might protect the heart better.

People born with certain gene changes that lower their bad cholesterol over their whole life have a lower chance of heart disease — the more their cholesterol is lowered, the lower their risk.

White adults with a certain gene variant have lower bad cholesterol and are nearly half as likely to get heart disease over 15 years — showing that even a small, lifelong drop in cholesterol can really protect your heart.