A certain genetic trait that usually raises heart disease risk doesn't seem to shorten life in very old French people, showing it might not always be bad for living a long life.

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Pro

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Against

Evidence from Studies

Supporting (1)

20

Community contributions welcome

20

Elevated lipoprotein(a) levels and small apo(a) isoforms are compatible with longevity: evidence from a large population of French centenarians.

Cross-Sectional Study

Human

The study looked at the same genetic trait in the same group of very old people and found that having this trait doesn't stop them from living a long life, which matches the claim exactly.

Contradicting (0)

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Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Elevated lipoprotein(a) levels and small apo(a) isoforms are compatible with longevity: evidence from a large population of French centenarians.

Score: 20

DOI: 10.1016/S0021-9150(97)00217-7

Similar Assertions

Even though high levels of a certain blood fat called Lp(a) are linked to heart problems in younger people, this study found that very old French people (over 100 years old) can have high Lp(a) and still live long lives.

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83%

In people who live to be 100 or older, both inherited traits and lifestyle factors seem to affect their lipoprotein(a) levels, showing that more than just genetics plays a role in these levels for long-lived individuals.

20

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82%