The Claim

Each additional teaspoon of artificial sweetener consumed daily is associated with a 1.2% increased risk of incident cardiovascular disease, a 1.8% increased risk of coronary artery disease, and a 3.5% increased risk of peripheral arterial disease in middle-aged and older adults, independent of lifestyle, metabolic, and genetic factors.

Source: Artificial sweeteners and risk of incident cardiovascular disease and mortality: evidence from UK Biobank

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
67score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

In middle-aged and older adults, consuming one more teaspoon of artificial sweetener per day is linked to higher rates of cardiovascular disease, coronary artery disease, and peripheral arterial disease.

See the scientific wording

Each additional teaspoon of artificial sweetener consumed daily is associated with a 1.2% increased risk of incident cardiovascular disease, a 1.8% increased risk of coronary artery disease, and a 3.5% increased risk of peripheral arterial disease in middle-aged and older adults, independent of lifestyle, metabolic, and genetic factors, suggesting a consistent link between low-calorie sweetener intake and vascular health risks.

Why this might work

When people consume artificial sweeteners, the chemicals change the bacteria in the gut, which causes the body to release more insulin even when there is no sugar to process. Over time, this makes the body less able to control blood sugar, leading to high blood sugar levels that damage the lining of blood vessels. This damage causes inflammation and thickening of artery walls, which blocks blood flow and leads to heart attacks, strokes, and poor circulation in the legs.

Supported mechanismbased on 1 study

What the research says

1 study
  1. Study: Artificial sweeteners and risk of incident cardiovascular disease and mortality: evidence from UK Biobank

    This study found that people who add one more teaspoon of artificial sweetener each day have a tiny but real increase in their risk of heart and artery problems over time, even if they’re healthy, fit, or don’t have a family history of heart disease. The sweetener might be causing harm by increasing diabetes risk, which then leads to heart issues.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.