People who are overweight or obese tend to have less of a specific fat-related chemical (15-HETE) in their blood than lean people, and the more weight they have, the less of this chemical they have.

The study found that people who are heavier (have higher BMI) tend to have less of a chemical called 15-HETE in their blood, which matches the claim that higher body weight is linked to lower levels of this substance.