The Claim

The acute phosphorylation of p70S6K at 5 hours post-exercise is associated with greater muscle hypertrophy following 16 weeks of resistance training in young men, indicating that the timing and magnitude of this intracellular signaling event may be a biomarker of individual training responsiveness.

Source: Muscular and Systemic Correlates of Resistance Training-Induced Muscle Hypertrophy

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
39score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

When young men lift weights, if a specific protein in their muscles gets activated strongly exactly 5 hours after working out, they tend to build more muscle over the next 4 months—so this protein spike might tell us who’s going to grow the most from training.

See the scientific wording

The acute phosphorylation of p70S6K at 5 hours post-exercise is associated with greater muscle hypertrophy following 16 weeks of resistance training in young men, indicating that the timing and magnitude of this intracellular signaling event may be a biomarker of individual training responsiveness.

What the research says

1 study
  1. Study: Muscular and Systemic Correlates of Resistance Training-Induced Muscle Hypertrophy

    The study found that when guys’ muscles showed a strong signal (p70S6K phosphorylation) 5 hours after working out, they tended to grow bigger muscles after 16 weeks of training — so this signal might help predict who responds well to lifting weights.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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