The Claim

One year after treatment cessation, individuals who previously received supervised exercise (with or without liraglutide) engaged in higher levels of moderate-to-vigorous physical activity compared to individuals who received liraglutide alone or placebo.

Source: Healthy weight loss maintenance with exercise, GLP-1 receptor agonist, or both combined followed by one year without treatment: a post-treatment analysis of a randomised placebo-controlled trial

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
34score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

One year after stopping treatment, people who had done supervised exercise during their treatment were more active in moderate-to-vigorous physical activity than those who only took liraglutide or a placebo.

See the scientific wording

One year after treatment cessation, participants who previously received supervised exercise (with or without liraglutide) engaged in significantly more moderate-to-vigorous physical activity than those who received liraglutide alone or placebo, suggesting exercise training may promote lasting behavioral change.

Why this might work

Repeated physical activity during supervised training strengthens brain circuits that make movement automatic, so people keep being active even after the program ends. This keeps their metabolism high and prevents weight gain, while stopping a weight-loss drug causes hunger to surge and energy use to drop, leading to rapid weight regain.

Verified mechanismbased on 1 study

What the research says

1 study
  1. Study: Healthy weight loss maintenance with exercise, GLP-1 receptor agonist, or both combined followed by one year without treatment: a post-treatment analysis of a randomised placebo-controlled trial

    People who did supervised exercise during the study stayed lighter a year after stopping, even though they weren’t being watched anymore — this suggests they kept being active on their own. Those who only took the weight-loss drug gained most of the weight back.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.