If someone has higher levels of certain sweetener-related chemicals in their blood, they might be more likely to have heart problems later—about 26% more likely, according to studies tracking people over time.

If you drink or eat more artificial sweeteners, you might have a slightly higher chance of heart problems over time, according to a big study of French adults.

We're not really sure if artificial sweeteners affect heart health because most studies only looked at certain foods, not overall intake, and there just aren't enough studies to be confident.

Eating artificial sweeteners doesn't show a clear link to heart‑related deaths or heart problems, according to studies that looked at what adults eat.

Drinking or eating a lot of artificial sweeteners might increase your chances of having a stroke or a mini-stroke, according to a study of over 100,000 French adults followed for nearly a decade.

Studies looking at sugar-related substances in the blood and heart problems don’t agree very well with each other — the results vary a lot, possibly because of different people, methods, or hidden factors.