Adults who maintain a large waist size over a two-year period have an 18% higher risk of developing colorectal cancer before age 50 compared to those who do not have persistent abdominal obesity.

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Evidence from Studies

Supporting (1)

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Community contributions welcome

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Association of changes in obesity and abdominal obesity status with early-onset colorectal cancer risk: a nationwide population-based cohort study

Cohort Study

Human

2023

People who kept having a large waistline over two years were 18% more likely to get colon cancer before age 50 than those who didn’t, according to a huge study of Korean adults.

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Source Study

Association of changes in obesity and abdominal obesity status with early-onset colorectal cancer risk: a nationwide population-based cohort study

Score: 59

DOI: 10.3389/fmed.2023.1208489

Similar Assertions

People who maintain a body mass index of 25 kg/m² or higher over a two-year period have a 9% higher risk of developing colorectal cancer before age 50 compared to those who maintain a non-obese weight.

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People who consistently have excess body weight and excess fat around the abdomen have a 19% higher chance of developing colorectal cancer before age 50 compared to people who maintain a normal weight and no abdominal fat accumulation.

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People who gain fat specifically around the abdomen after being previously lean have a slightly higher chance of developing colorectal cancer at a younger age than those who never gained excess weight.

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People with obesity have a higher chance of developing colorectal cancer compared to those without obesity, with men showing a greater increase in risk than women.

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People who had a high body mass index (BMI) 8 to 12 years before being diagnosed with colorectal cancer were more than twice as likely to develop the disease compared to those with a normal BMI, suggesting that carrying excess weight over a long period increases risk, even if weight drops shortly before diagnosis.

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78%