People who took tesamorelin felt better about how their belly looked, and doctors also thought their belly looked better — even though their outer fat didn’t change, just the inside fat.

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Evidence from Studies

Supporting (1)

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Effects of Tesamorelin, a Growth Hormone–Releasing Factor, in HIV-Infected Patients With Abdominal Fat Accumulation: A Randomized Placebo-Controlled Trial With a Safety Extension

Randomized Controlled Trial

Human

2010 Mar

The study found that a daily shot of tesamorelin helped HIV patients feel better about their belly appearance and made their belly look better to doctors — without changing the fat under the skin, just the deep belly fat.

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No contradicting evidence found

Source Study

Effects of Tesamorelin, a Growth Hormone–Releasing Factor, in HIV-Infected Patients With Abdominal Fat Accumulation: A Randomized Placebo-Controlled Trial With a Safety Extension

Score: 81

DOI: 10.1097/QAI.0b013e3181cbdaff

Similar Assertions

Patients who got the real injection felt better about how their belly looked, while those who got the fake shot didn’t.

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Doctors who didn’t know who got the real drug thought patients’ bellies looked better after treatment.

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The drug doesn’t make you lose fat from your skin or your arms and legs — it only targets the fat deep inside your belly, which is the kind that’s most dangerous.

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The drug shrinks the fat around the torso and makes the waist smaller, but doesn’t change the fat on the arms, legs, or just under the skin — meaning it targets only the dangerous internal fat.

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A daily injection called tesamorelin helps HIV patients with a big belly lose nearly 11% of their dangerous internal belly fat in six months, while those getting a fake shot don’t lose any.

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