The Claim

In Han Chinese individuals with essential hypertension, the rs434082 A allele in the SLC8A1 gene is associated with a 2.8 mm Hg increase in diastolic blood pressure and a 3.1 mm Hg increase in mean arterial pressure during acute oral sodium loading, after adjusting for age and 24-hour urinary sodium excretion.

Source: Genetic Variation in SLC8A1 Gene Involved in Blood Pressure Responses to Acute Salt Loading

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
41score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

In people of Han Chinese descent with high blood pressure, having a specific version of a gene (rs434082 A) seems to make their blood pressure rise a little more when they eat a lot of salt, even after accounting for how much salt they’ve excreted and their age.

See the scientific wording

In Han Chinese individuals with essential hypertension, the rs434082 A allele in the SLC8A1 gene is associated with a 2.8 mm Hg increase in diastolic blood pressure and a 3.1 mm Hg increase in mean arterial pressure during acute oral sodium loading, after adjusting for age and 24-hour urinary sodium excretion.

What the research says

1 study
  1. Study: Genetic Variation in SLC8A1 Gene Involved in Blood Pressure Responses to Acute Salt Loading

    Scientists gave salt to Chinese high-blood-pressure patients and found that those with a specific gene version (rs434082 A) had their blood pressure rise more than others — exactly what the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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